Colchicine is a medication that is used to treat gout, familial Mediterranean fever (FMF), and pericarditis. It is also used to prevent gout attacks in people who are at high risk. Colchicine works by interfering with the movement of white blood cells to the joints. This helps to reduce inflammation and pain. Colchicine is available in tablet and capsule form. It is typically taken once or twice daily. Colchicine can be used to treat acute gout attacks and to prevent gout attacks.