Brimonidine tartrate and timolol maleate is a combination medications used to treat elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension. This combination medication is often prescribed when single/agent therapy is not sufficient to adequately control intraocular pressure. As mentioned earlier, brimonidine tartrate is an alpha/2 adrenergic agonist that reduces the production of aqueous humor (the fluid within the eye) and increases its outflow to lower intraocular pressure. Timolol maleate is a beta/blocker that reduces the production of aqueous humor to achieve the same goal of lowering IOP. When used in combination, these two medications complement each other's mechanisms of action, leading to greater IOP reduction compared to using each medication alone. This combination approach can be particularly effective in cases where monotherapy is insufficient in managing glaucoma or ocular hypertension. The combination of brimonidine tartrate and timolol maleate is usually available in eye drop form. These eye drops are instilled directly into the eye, as instructed by your ophthalmologist or healthcare provider. It's important to follow the recommended dosage schedule and administration instructions to ensure that you receive the full benefit of the treatment.