 Aricept Description
Donepezil tablets, marketed under the trade name Aricept (Eisai), (Pfizer), is a centrally acting reversible acetylcholinesterase inhibitor , used in the treatment of Alzheimer's disease . It is used to increase cortical acetylcholine. Its binding to the acetylcholinesterase can be seen at Proteopedia 1eve. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a half life of about 70 hours, it can be taken once a day. Initial dose is 5 mg per day, which can be increased to 10 mg per day after an adjustment period of at least 4 weeks.
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Indication:
Aricept used in the treatment of Alzheimer's disease, is postulated to exert it therapeutic effect by enhancing the colinergic function. This is acompalished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. It does not alter the course of underlying dementing process.Aricept avilable in 5mg (white) and 10 mg (yellow)can be purcahsed either from the nearest pharmacy or can also be bought at a very economical price from Online Canada Pharmacy.The drug not only will be delivered at your door step but also will be of same efficacy as one bought from the local pharmacy and you will be paying about 29 percent less price than the former making the candian online pharmacy more lucrative you.
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Dosage:
Aricept taken orally is avialable for oral administration in film coated tablets containing 5 or 10 mg of donepezil hydorchloride .Inactive ingredients are lactose monohydrate, corn strach, microcrystalline cellulose, hydroxypropyl cellulose and magnesium stearate. The film coating contains talc, polyethylene glycol, and hypromellose and titanium disoxide. Additionaly the 10 mg tablet contains yellow iron oxide (synthetic) as coloring agent.
Aricpet ODT tablets have inactive ingredients as carrageenan, mannitol, colloidal silicon dioxide and poyvinyl alcohol. Additionaly the 10 mg tablet contains ferric oxide (yellow) as coloring agent.
Aricept is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. It is well absorbed in the gut with an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a half life of about 70 hours, it can be taken once a day. Initial dose is 5 mg per day, which can be increased to 10 mg per day after an adjustment period of at least 4 weeks. Aricept is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Aricept is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase.
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Precautions:
ARICEPT? is reported to be contraindicated in patients with known hypersensitivity to donepezil hydrochloride or to piperidine derivatives. Drugs that inhibit or Induce CYP 2D6 and CYP 3A4 may affect the concentration on Aricept .It can interact with certain medications. Aricept may interact with some of the medicines used during surgery or dental procedures and cause unwanted side effects. Aricept may cause dizziness or drowsiness, or have blurred vision. People under this medication should take precaution while driving or operating heavy machines. Aricept may cause hypotension (low blood pressure) and make patient feel light-headed when they stand. Patient must make sure to rise slowly from a sitting or lying position. Aricept may make certain heart conditions worse like sick sinus syndrome, heart block, or other heart problems, If patient is taking Aricept and has an ulcer disease or is taking a nonsteroidal anti-inflammatory drug (NSAID), such as ibuprofen (Advil?, Motrin?), naproxen (Naprosyn?, Anaprox?, Naprelan Aleve?), or others, he/she may be at an increased risk for stomach or intestinal bleeding. Aricept should be used with caution in people with asthma, chronic obstructive pulmonary disease (COPD), or other obstructive-type lung diseases. Aricept has the potential to cause seizures (convulsions). However, if there is a seizure activity may also be because of Alzheimer's disease if patient has a seizure disorder or had a head injury or unstable metabolic conditions, caution should be taken while taking Aricept and report any seizures should be reported to the healthcare provider. Aricept may be the cause of bladder obstruction (which causes difficulty passing urine). If patient has any kind of bladder problem Aricept may the condition worse. It is important for your healthcare provider may choose to monitor your condition more closely. Aricept is a pregnancy Category C medicine. This means it may not be safe for use during pregnancy, although the full risks are not currently known.
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Side effects:
ARICEPT (donepezil HCl) is a drug which is well tolerated but may not be for everyone. It has been observed that some people may experience nausea, diarrhea, insomnia, vomiting, muscle cramps, fatigue or loss of appetite. In studies, these side effects were found to be usually mild and temporary. Some people taking ARICEPT (donepezil HCl) may experience fainting. People who are at risk for ulcers should tell their doctors because their condition may get worse The drug purchased from online Canadian Pharmacy is of same efficacy as one from the near by pharmacy and also economical and genuine which makes the physicians recommend our online Canadian Pharmacy.
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