 Description:
CASODEX? (bicalutamide) Tablets contain 50 mg of bicalutamide, a non-steroidal androgen receptor inhibitor with no other known endocrine activity. Casodex is an anti-androgen. It works in the body by preventing the actions of androgens (male hormones). Casodex is a hormone therapy. It is classified as an "anti-androgen." Often given in combination with "LHRH agonist," another type of hormone therapy. Antiandrogens are usually given with LHRH agonists (leutenizing hormone - releasing hormone). LHRH agonists work by telling the pituitary gland located in the brain to stop producing leutinizing hormone, which (in men) stimulates the testicles to release testosterone and (in women) stimulates the ovaries to release estrogen. The drug does not have a direct effect on the cancer, only on the testicles or ovaries. The resulting lack of testosterone (in men) and estrogen (in women) interferes with stimulating cell growth in testosterone or estrogen dependent cancer cells.
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Indication:
Casodex therapy is prescribed for men with advanced prostate cancer at stage D2, when there is evidence of metastases (cancer spread) to other areas of the body. The drug is available in form of tablets of 50mg ( taken once daily) and can be purchased either form the nearest pharmacy or can be ordered from the online Canada pharmacy which will make that available at your door step at a very economical price.The same efficacy and it being highly economical makes the drugs available from online pharmacy as the first choice by the physicians .
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Dosage:
Casodex is available in form of white film coated tablets of 50 mg, having bicalutamide as the active ingredient. The route of administration is oral. Hormone therapy works by stopping the production of a certain hormone, blocking hormone receptors, or substituting chemically similar agents for the active hormone, which cannot be used by the tumor cell. Different types of hormone therapies are categorized by their function and/or the type of hormone that is affected. Casodex is categorized as an antiandrogen. Antiandrogens are substances that block the effects of testosterone. Cancer of the prostate depends on the male hormone testosterone for its growth. If the amount of testosterone is reduced it is possible to slow down or shrink the cancer. Antiandrogens are usually given with LHRH agonists (leutenizing hormone - releasing hormone). LHRH agonists work by telling the pituitary gland located in the brain to stop producing leutinizing hormone, which (in men) stimulates the testicles to release testosterone and (in women) stimulates the ovaries to release estrogen. The drug does not have a direct effect on the cancer, only on the testicles or ovaries. The resulting lack of testosterone (in men) and estrogen (in women) interferes with stimulating cell growth in testosterone or estrogen dependent cancer cells.
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Precautions:
Before starting casodex treatment physician must be informed of any other medication if taken( including prescription , over the counter, vitamins ,herbal remedies etc). In case of diabetic patients serum glucose should be carefully monitored.Generally this medication is given to males howerever if is recommended to females then it should be ensured that she is not pregnant or planning to get pregnant or she should not be lactating aswell. The prescribed dose must be taken once a day daily at the same time with or without food and should not be discontinued without informing the doctor. The urinary bladder must be emptied before taking the tablet. Casodex therapy is to be taken with LHRH therapy. Also the while taking the medication good nutrituious diet should be taken and intake of alcholic breverages should be brought to minimum.
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Side effects:
Unlike other medication Casodex too is not an excpetion and few side effects have been reported in certain patients. The common side effects may include hot flashes, swelling of breasts( gynecomastia), breast pain, loss of libido( intrest in sex) and inability to obtain or sustain errection, loss of fertility. Besides these constipation, diarrhoea, and nausea too may be seen in some cases.
Elevated levels of tests ( liver function test ) too can be seen which comes to normal once medication is withdrawn. If any of these symtoms is felt or some other unusal compilcation is seen then physician must be consulted immidieatley.
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